Preoperative accelerated radiotherapy combined with chemotherapy in a defined cohort of patients with high risk soft tissue sarcoma: a Scandinavian Sarcoma Group study.
Kirsten Sundby HallØyvind S BrulandBodil BjerkehagenElisabet LidbrinkNina JebsenHans HagbergKarin PapworthOskar HagbergClement TrovikHenrik BauerMikael ErikssonPublished in: Clinical sarcoma research (2020)
Preoperative chemotherapy and radiotherapy were associated with temporary wound-healing problems. Survival outcomes, local control and toxicities were deemed satisfactory when considering the locally advanced sarcoma disease status at primary diagnosis. Trial registration This study was registered at ClinicalTrials.gov Identifier NCT00790244 and with European Union Drug Regulating Authorities Clinical Trials No. EUDRACT 2007-001152-39.
Keyphrases
- locally advanced
- rectal cancer
- clinical trial
- neoadjuvant chemotherapy
- squamous cell carcinoma
- radiation therapy
- phase ii study
- patients undergoing
- wound healing
- phase ii
- mental health
- phase iii
- study protocol
- open label
- early stage
- emergency department
- radiation induced
- adverse drug
- electronic health record
- chemotherapy induced