FGF8 induces therapy resistance in neoadjuvantly radiated rectal cancer.

Felix HarpainMohamed A AhmedXenia HudecGerald TimelthalerGerd JomrichLeonhard MüllauerEdgar SelzerWolfgang DörrMichael BergmannKlaus HolzmannBettina Grasl-KrauppMichael GruschWalter BergerBrigitte MarianGerd R Silberhumer

Published in: Journal of cancer research and clinical oncology (2018)

The results of this study suggest that FGF8 and Survivin contribute to radiation resistance in rectal cancer and may serve as markers to select patients who may not benefit from neoadjuvant radiotherapy.

Keyphrases

rectal cancer
locally advanced
squamous cell carcinoma
radiation therapy
early stage
radiation induced
lymph node
bone marrow