Clinical outcomes of left atrial appendage occlusion in patients with previous intracranial or gastrointestinal bleeding: Insights from the LOGIC (Left atrial appendage Occlusion in patients with Gastrointestinal or IntraCranial bleeding) International Multicenter Registry.
Francesco GalloFederico RoncoGianpiero D'AmicoDomenico G Della RoccaPatrizio MazzoneStefano BordignonGavino CasuFrancesco GianniniSergio BertiRodney P HortonGiuseppe D'AngeloLukas UrbanekPierluigi MerellaRossella RuggieroMaria Rita RomeoFrancesco BosicaBoris SchmidtEnrico AtzoriMarco BarbieratoAndrea NataleSakis ThemistoclakisPublished in: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions (2023)
Outcomes after LAAO may be affected by the different indications for the procedure. In our study, GI-bleeding and IC-bleeding as indication to LAAO differ in their baseline characteristics. LAAO confirms its efficacy in ischemic risk reduction in both groups, while GI bleeding seems to be an independent predictor of bleeding recurrence at 12 months behind the antithrombotic regimen.