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Contrasting effects of the alkaloid ricinine on the capacity of Anopheles gambiae and Anopheles coluzzii to transmit Plasmodium falciparum.

Domonbabele F D S HienPrisca S L ParéAmanda CooperBenjamin K KoamaEdwige GuissouKoudraogo B YaméogoRakiswendé S YerbangaIain W FarrellJean B OuédraogoOlivier GnankinéRickard IgnellAnna CohuetRoch K DabiréPhilip C StevensonThierry Lefèvre
Published in: Parasites & vectors (2021)
Overall, our findings reveal that consumption of certain nectar phytochemicals can have unexpected and contrasting effects on key phenotypic traits that govern the intensity of malaria transmission. Further studies will be required before concluding on the putative role of ricinine as a novel control agent, including the development of ricinine-based toxic and transmission-blocking sugar baits. Testing other secondary phytochemicals in plant nectar will provide a broader understanding of the impact which plants can have on the transmission of vector-borne diseases.
Keyphrases
  • plasmodium falciparum
  • genome wide
  • aedes aegypti
  • gene expression
  • dna methylation
  • zika virus
  • cell wall