Aperiodic neural activity is a biomarker for depression severity.
Carl D HackerM M MocchiJiayang XiaoBrian A MetzgerJ A AdkinsonB R PascuzziR C MathuraDenise OswaltAndrew J WatrousEleonora BartoliAnusha AllawalaV PirtleXiaoxu FanI DanstromB ShoftyGarrett P BanksY ZhangM Armenta-SalasK MirpourNicole R ProvenzaSanjay J MathewJeffrey F CohnDavid A BortonW GoodmanN PouratianSameer A ShethKelly R BijankiPublished in: medRxiv : the preprint server for health sciences (2023)
The aperiodic component of the power spectral density robustly tracks depression severity on the order of minutes to hours.