Effect of active immunization with IL-17A on B cell function and infection risk in pristane-induced lupus model.

Kusworini HandonoMirza Zaka PratamaDita Kartika SariHanestya Oky HermawanHafishtyawan Maulidyananta AgdanaKeryasta Becik KawuninganNafisah Nur'ainiDian HasanahHandono Kalim

Published in: International journal of rheumatic diseases (2018)

Active immunization with IL-17A coupled to KLH was able to induce a high titer of neutralizing antibodies against IL-17A and inhibit B cell functions without increasing the risk of infection in a pristane-induced lupus mice model.

Keyphrases

systemic lupus erythematosus
high glucose
diabetic rats
disease activity
endothelial cells
rheumatoid arthritis
adipose tissue
dengue virus
insulin resistance
high fat diet induced
stress induced