EGFR and ERBB2 Exon 20 Insertion Mutations in Chinese Non-small Cell Lung Cancer Patients: Pathological and Molecular Characterization, and First-Line Systemic Treatment Evaluation.

Ruiying ZhaoJiaqi LiLianying GuoChan XiangShengnan ChenJikai ZhaoJinchen ShaoLei ZhuMin YeGang QinTianqing ChuYuchen Han

Published in: Targeted oncology (2024)

EGFR/ERBB2-20ins is more common in early lung adenocarcinoma. EGFR-20ins had more variants. In both cohorts, the results for first-line systemic treatments showed no significant difference.

Keyphrases

tyrosine kinase
small cell lung cancer
epidermal growth factor receptor
single cell
copy number
cell therapy
stem cells
gene expression
dna methylation
genome wide
drug induced
smoking cessation