Asymmetric organocatalytic Michael addition of cyclopentane-1,2-dione to alkylidene oxindole.

Published in: Beilstein journal of organic chemistry (2022)

An asymmetric Michael reaction between cyclopentane-1,2-dione and alkylidene oxindole was studied in the presence of a multifunctional squaramide catalyst. Michael adducts were obtained in high enantioselectivities and in moderate diastereoselectivities.

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