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Therapeutic Function of Liraglutide for Mitigation of Blast-Induced Hearing Damage: An Initial Investigation in Animal Model of Chinchilla.

Shangyuan JiangSarah SandersPaige WelchRong Z Gan
Published in: Military medicine (2024)
This study indicated that the liraglutide mitigated the blast-induced auditory injuries. In EP ears, the pre-blast administration of liraglutide reduced the severity of blast-induced acute damage in ears with EP protection, especially under G2. In animals with open ears, the effect of liraglutide on the restoration of hearing increased with time. The liraglutide potentially benefits post-blast hearing through multiple approaches with different mechanics.
Keyphrases
  • hearing loss
  • high glucose
  • diabetic rats
  • oxidative stress
  • drug induced
  • minimally invasive