In vitro Multistage Malaria Transmission Blocking Activity of Selected Malaria Box Compounds.
Hamisi M MaleboSarah D'AlessandroYehenew A EbstieHarouna SorèAlain R Tenoh GuedoungShaaban J KataniSilvia ParapiniDonatella TaramelliAnnette HabluetzelPublished in: Drug design, development and therapy (2020)
Given the multi-stage, transmission-blocking profiles of MMV000642, MMV000662, MMV006429, and their chemical characteristics, these compounds can be considered worthy for further optimisation toward a TCP5 or TCP6 target product profile proposed by MMV for transmission-blocking antimalarials.
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