Biomarkers from circulating neutrophil transcriptomes have potential to detect unruptured intracranial aneurysms.
Vincent M TutinoKerry E PoppenbergLu LiHussain ShallwaniKaiyu JiangJames N JarvisYijun SunKenneth V SnyderElad I LevyAdnan H SiddiquiJohn KolegaVincent M TutinoPublished in: Journal of translational medicine (2018)
Our findings demonstrate the potential of machine-learning methods to classify IA cases and create predictive models for unruptured IAs using circulating neutrophil transcriptome data. Future studies are needed to replicate these findings in larger cohorts.