Combining structural and metabolic markers in a quantitative MRI study of motor neuron diseases.
Antonietta CannaFrancesca TrojsiFederica Di NardoGiuseppina CaiazzoGioacchino TedeschiMario CirilloFabrizio EspositoPublished in: Annals of clinical and translational neurology (2021)
While increased QSM values in the motor cortex of ALS patients is a consolidated finding, combining QSM, CBF, and GM volumetry shows higher diagnostic potential for differentiating ALS patients from HC subjects and, in the motor cortex, between ALS and PLS.