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Effects of lixisenatide on postprandial blood pressure, gastric emptying and glycaemia in healthy people and people with type 2 diabetes.

Karen Louise JonesRachael S RigdaMadeline D M ButtfieldSeva HatzinikolasHung T PhamChinmay S MaratheChinmay S MaratheKylie LangeLaurence G TrahairChristopher K RaynerMichael Horowitz
Published in: Diabetes, obesity & metabolism (2019)
In healthy participants and those with T2DM, the marked slowing of gastric emptying of glucose induced by lixisenatide was associated with attenuation of the increments in glycaemia and SMA flow and decrease in systolic BP. Accordingly, lixisenatide may be useful in the management of postprandial hypotension.
Keyphrases
  • blood pressure
  • blood glucose
  • glycemic control
  • hypertensive patients
  • heart failure
  • heart rate
  • left ventricular
  • type diabetes
  • adipose tissue
  • metabolic syndrome
  • skeletal muscle