Effects of lixisenatide on postprandial blood pressure, gastric emptying and glycaemia in healthy people and people with type 2 diabetes.
Karen Louise JonesRachael S RigdaMadeline D M ButtfieldSeva HatzinikolasHung T PhamChinmay S MaratheChinmay S MaratheKylie LangeLaurence G TrahairChristopher K RaynerMichael HorowitzPublished in: Diabetes, obesity & metabolism (2019)
In healthy participants and those with T2DM, the marked slowing of gastric emptying of glucose induced by lixisenatide was associated with attenuation of the increments in glycaemia and SMA flow and decrease in systolic BP. Accordingly, lixisenatide may be useful in the management of postprandial hypotension.