Transcutaneous CO2 application accelerates fracture repair in streptozotocin-induced type I diabetic rats.

Takahiro Oda Takahiro NiikuraTomoaki FukuiKeisuke OeYu KuroiwaYohei KumabeKenichi SawauchiRyo YoshikawaYutaka MifuneShinya HayashiTomoyuki MatsumotoTakehiko MatsushitaTeruya KawamotoYoshitada SakaiToshihiro AkisueRyosuke Kuroda

Published in: BMJ open diabetes research & care (2021)

Our findings suggest that CO2 treatment accelerates fracture repair in type I DM rats. CO2 treatment could be an effective strategy for delayed fracture repair due to DM.

Keyphrases

diabetic rats
oxidative stress
high fat diet
type diabetes
metabolic syndrome
hip fracture
adipose tissue
insulin resistance
smoking cessation