The epithelial-to-mesenchymal transition induced by tumor-associated macrophages confers chemoresistance in peritoneally disseminated pancreatic cancer.
Kazuya KuwadaShunsuke KagawaRyuichi YoshidaShuichi SakamotoAtene ItoMegumi WatanabeTakeshi IedaShinji KurodaSatoru KikuchiHiroshi TazawaToshiyoshi FujiwaraPublished in: Journal of experimental & clinical cancer research : CR (2018)
Intraperitoneal tumor-associated macrophages potentially play an important role in promotion of peritoneal dissemination and chemoresistance of pancreatic cancer via EMT induction.