Localization and characterization of human papillomavirus-16 in oral squamous cell carcinoma.
Wafaa SalehSeunghee ChaAbdulaziz BanasserSarah G FitzpatrickIndraneel BhattacharyyaJilan M YoussefMohamed M AneesIslam A ElzahabyJoseph KatzPublished in: Oral diseases (2021)
HPV-16 is a significant factor in oral carcinogenesis. We recommend using p16INK4A as a surrogate marker for HPV detection in OSCC, which can be complemented by RNA ISH for the identification of HPV subtypes.