Diverse associations observed between pregnancy complications and RBC or plasma folates determined by an in-house developed LC-MS/MS method.

Zhengwen XuYouran LiYing LiuShengmin LiuLin ZhangJing WangShaofei SuLin LiuLanlan MengHongyuan ZhuJingru SunLijun ShaoLin LiYanhong ZhaiGuanghui LiZheng Cao

Published in: Annals of medicine (2023)

The in-house developed LC-MS/MS method for folates and metabolites in plasma or RBC showed satisfactory analytical performance for clinical application. Further, the levels of folates and metabolites were diversely associated with GDM, GH and PE development.

Keyphrases

ms ms
red blood cell
preterm birth
liquid chromatography
mass spectrometry
simultaneous determination
pregnant women
high resolution
tandem mass spectrometry
gas chromatography