Fabrication of a novel graphene oxide based magnetic nanocomposite and its usage as a highly effectual catalyst for the construction of N , N '-alkylidene bisamides.

At first, a novel graphene oxide-based magnetic nanocomposite namely Si-propyl-functionalized N 1 , N 1 , N 2 , N 2 -tetramethylethylenediamine- N 1 , N 2 -diium hydrogen sulfate anchored to graphene oxide-supported Fe 3 O 4 (nano-[GO@Fe 3 O 4 @R-NHMe 2 ][HSO 4 ]) was fabricated. After full characterization of the nanocomposite, its catalytic performance was examined for the solvent-free construction of N , N '-alkylidene bisamides from aryl aldehydes (1 eq.) and primary aromatic and aliphatic amides (2 eq.), in which the products were acquired in short times (15-30 min) and high to excellent yields (89-98%). Nano-[GO@Fe 3 O 4 @R-NHMe 2 ][HSO 4 ] could be magnetically isolated form the reaction medium, and reused three times without remarkable loss of catalytic activity.