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Impact of pathological tumor response after CROSS neoadjuvant chemoradiotherapy followed by surgery on long-term outcome of esophageal cancer: a population-based study.

Ali Al-KaabiRachel S van der PostLeonie R van der WerfBas P L WijnhovenCamiel RosmanMaarten C C M HulshofHanneke W M van LaarhovenRob H A VerhoevenPeter Derk Siersema
Published in: Acta oncologica (Stockholm, Sweden) (2021)
In this population-based study, pathological tumor response based on the ypTNM-stage was associated with different prognostic subgroups. A quarter of patients achieved ypT0N0 with favorable long-term survival, while one-third had an ypT+N+ response with very poor survival. The association between pathological tumor response and long-term survival could help in more accurate assessments of individual prognosis and treatment decisions.
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