Comprehensive Genomic Characterization of Parathyroid Cancer Identifies Novel Candidate Driver Mutations and Core Pathways.

Callisia N ClarkePanagiotis KatsonisTeng-Kuei HsuAmanda M KoireAngelica Silva-FigueroaIoannis ChristakisMichelle D WilliamsMerve KutahyaliogluLily KwatamporaYuanxin XiJeffrey E LeeE Scott KoptezNaifa L BusaidyNancy D PerrierOlivier Lichtarge

Published in: Journal of the Endocrine Society (2018)

We identified 33 candidate driver genes of sporadic PC, in addition to previously known driver genes CDC73 and MEN1.

Keyphrases

genome wide
papillary thyroid
bioinformatics analysis
copy number
dna methylation
late onset
squamous cell
cell cycle
middle aged
gene expression
amyotrophic lateral sclerosis
squamous cell carcinoma
lymph node metastasis