Sphingosine-1-phosphate alleviates irradiation-induced parotid injury in a miniature pig model.

Wen PanLiang HuYawen ChenZhao ZhuYingxin WangJiaxin SongZhaochen Shan

Published in: Oral diseases (2020)

Sphingosine-1-phosphate may partially alleviate IR-induced parotid dysfunction by decreasing apoptosis of microvascular endothelial cells and maintaining the blood flow rate.

Keyphrases

high glucose
blood flow
endothelial cells
oxidative stress
diabetic rats
drug induced
signaling pathway
cell proliferation
vascular endothelial growth factor
stress induced
pi k akt