Dolabellane Diterpenes and Elemane Alkaloids from the Soft Coral Clavularia inflata Collected in the South China Sea.

Five new dolabellane diterpenes, clavularinlides A-E ( 1 - 5 ), and four new racemic elemane alkaloids, clavulacylides A-D ( 7 - 10 ), together with one known compound ( 6 ), were isolated from the soft coral Clavularia inflata collected in the South China Sea. Their structures were elucidated by 1D and 2D NMR, HRESIMS, calculated ECD, and DP4+ probability analyses. Compounds 1 - 7 showed anti-inflammatory activity in the zebrafish assay.