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Genetic and phenotypic frequency distribution of CYP2C9, CYP2C19 and CYP2D6 in over 3200 Han Chinese.

Li HeShaojun ChenJingao LiXiaoxue XieLihua HuangYun KuangKangwei XuWanxia HuangYanling ZhaoGuo-Ping YangCheng-Xian Guo
Published in: Clinical and experimental pharmacology & physiology (2020)
Polymorphisms and phenotypic changes of CYP2C9, CYP2C19 and CYP2D6 are relatively frequent in the Han Chinese population. Thus, preemptive pharmacogenetic testing of CYP2C9, CYP2C19 and CYP2D6 should be recommended prior to dosing substrate drugs.
Keyphrases
  • gene expression
  • dna methylation
  • drug induced
  • amino acid