Protective Role of MerTK in Diabetic Peripheral Neuropathy via Inhibition of the NF-κB Signaling Pathway.

Xiaoyang SuWenting ChenYidan FuBian WuFugang MaoYan ZhaoQiuping YangDanfeng Lan

Published in: Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association (2024)

Inhibition of MerTK exacerbates neuropathy, indicating its protective role in DPN by suppressing the NF-κB pathway, highlighting a potential new target for its diagnosis and treatment.

Keyphrases

signaling pathway
pi k akt
lps induced
induced apoptosis
epithelial mesenchymal transition
type diabetes
nuclear factor
oxidative stress
cell proliferation
wound healing
inflammatory response