ASSOCIATION OF PROMOTER REGION POLYMORPHISMS OF INTERLEUKIN-10 GENE WITH SUSCEPTIBILITY TO COLORECTAL CANCER: A SYSTEMATIC REVIEW AND META-ANALYSIS.

Seyed Alireza MirjaliliMansour MoghimiKazem AghiliMohammadali JafariSeyed Mojtaba AbolbaghaeiHossein NeamatzadehMahta MazaheriMasoud Zare-Shehneh

Published in: Arquivos de gastroenterologia (2019)

In this meta-analysis we found that IL-10 -819T>C polymorphism was associated with significantly increased risk of CRC; while the IL-10 -1082A>G and -592C>A polymorphisms were not associated with CRC risk. The IL-10 -819T>C polymorphism may be important as suspected predictive factor of CRC occurrence.

Keyphrases

systematic review
dna methylation
risk assessment
transcription factor
pulmonary embolism
genome wide
meta analyses