Docetaxel-Induced Stevens-Johnson Syndrome in a Patient with Metastatic Prostate Adenocarcinoma.
Osama DiabDan McentireThamer KassimAli NayfehAbdel Rahman DajaniMitchell KerfeldJonathon CampbellAdbullah AlsuwaidanMahmoud Abu HazeemMaryam Gbadamosi-AkindelePublished in: Case reports in oncological medicine (2019)
Docetaxel is a commonly used chemotherapeutic agent in a variety of cancer treatment regimens. We present a case of apparent docetaxel-induced Stevens-Johnson syndrome (SJS) in a patient recently treated for metastatic prostate cancer. This medication is not classically associated with the development of SJS but in our case, along with a number of other case reports, and a single phase II clinical trial, an association was recognized. We encourage clinicians who employ the use of this medication to be aware of this relationship.
Keyphrases
- case report
- prostate cancer
- phase ii
- clinical trial
- squamous cell carcinoma
- locally advanced
- open label
- high glucose
- small cell lung cancer
- diabetic rats
- healthcare
- radical prostatectomy
- drug induced
- adverse drug
- palliative care
- phase iii
- rectal cancer
- oxidative stress
- double blind
- emergency department
- placebo controlled
- contrast enhanced
- stress induced