Genetic Polymorphisms in Glutathione S-Transferase (GST) Gene and Their Correlation with Toxicity of Chemotherapy in Breast Cancer Patients.

Rashmi A GudurSuresh J BhosaleAnand K GudurKailas D Datkhile

Published in: Asian Pacific journal of cancer prevention : APJCP (2024)

The findings obtained from this study proposed significant involvement of GSTT1-null genotype in hematological neutropenia toxicity in response to Adriamycin and GSTM1-null genotype showed negative association with non-hematological toxicity (bodyache) in response to Paclitaxel.

Keyphrases

oxidative stress
chemotherapy induced
oxide nanoparticles
radiation therapy
transcription factor