Statins and Gliomas: A Systematic Review of the Preclinical Studies and Meta-Analysis of the Clinical Literature.
Luis F RendonIshaan Ashwini TewarieDavid J CoteAaron GabrielTimothy R SmithMarike L D BroekmanRania A MekaryPublished in: Drugs (2022)
Statins were potent anti-cancer drugs that suppressed glioma growth through various mechanisms in vitro; these effects have translated into the clinical realm, clinically but not statistically, in terms of glioma incidence but not GBM survival.