Factors predicting disease progression in C9ORF72 ALS patients.

Jessica MandrioliElisabetta ZucchiIlaria MartinelliLaura Van der MostGiulia GianferrariCristina MogliaUmberto ManeraLuca SoleroRosario VastaAntonio CanosaMaurizio GrassanoMaura BrunettiLetizia MazziniFabiola De MarchiCecilia SimoniniNicola FiniRossella TuplerMarco VincetiAdriano ChiòAndrea Calvo

Published in: Journal of neurology (2022)

Even in the context of a more aggressive disease, C9 + ALS had a longer survival in presence of thyroid disorders. This finding may suggest protective pathogenic pathways in C9 + ALS to be explored, looking for therapeutic strategies to slow disease course.

Keyphrases

amyotrophic lateral sclerosis
end stage renal disease
ejection fraction
chronic kidney disease
newly diagnosed
prognostic factors
free survival