Peripheral immunity changes are associated with neurodegeneration and worse clinical outcome in idiopathic normal pressure hydrocephalus.

Jacopo BissaccoClara SimonettaDavide MascioliHenri ZenuniRoberta BovenziPiergiorgio GrilloFrancesca Di GiulianoAlessandro StefaniNicola Biagio MercuriTommaso Schirinzi

Published in: European journal of neurology (2023)

iNPH patients present a proinflammatory state associated with neurodegeneration and predicting poor clinical outcome. Systemic inflammation represents a factor in the clinical-pathological progression of iNPH, and the NLR emerges as a potential prognostic index.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
prognostic factors
peritoneal dialysis
subarachnoid hemorrhage
risk assessment
patient reported