Characterization and modulation of endoplasmic reticulum stress response target genes in Kluyveromyces marxianus to improve secretory expressions of heterologous proteins.

Tianfang ShiJungang ZhouAijuan XueHong LuYungang HeYao Yu

Published in: Biotechnology for biofuels (2021)

Our results unveil the transcriptional scope of the ER stress response in K. marxianus and suggest efficient ways to improve productions of heterologous proteins by manipulating expressions of ESRTs.

Keyphrases

endoplasmic reticulum stress
induced apoptosis
saccharomyces cerevisiae
gene expression
transcription factor
genome wide
bioinformatics analysis