Vancomycin-Induced Changes in Host Immunity and Behavior: Comparative Genomic and Metagenomic Analysis in C57BL/6 and BALB/c Mice.
Pratikshya RayUday PandeyDebasmita DasPalok AichPublished in: Digestive diseases and sciences (2021)
The results revealed that the gut microbiome profiling, behavior, and immune responses varied significantly between Th1- and Th2-biased mice. By withdrawing the treatment with vancomycin of major gut microbes, important physiological and behavioral changes of both mice strains returned to the normal (untreated control) level.
Keyphrases
- high fat diet induced
- immune response
- escherichia coli
- methicillin resistant staphylococcus aureus
- single cell
- type diabetes
- gene expression
- insulin resistance
- wild type
- copy number
- dna methylation
- skeletal muscle
- wastewater treatment
- genome wide
- antibiotic resistance genes
- combination therapy
- inflammatory response