Transcriptional pathways across colony biofilm models in the symbiont Vibrio fischeri .
Jacob A Vander GriendRuth Y IsenbergKetan R KotlaMark J MandelPublished in: mSystems (2023)
biofilm models followed by phenotypic validation and examination of novel signaling pathway architecture. Remarkable consistency between the models provides a strong basis for future studies using either approach or both. A subset of the factors identified by the approaches were validated in the work, and the body of transcriptomic data provides a number of leads for future studies in culture and during animal colonization.
Keyphrases
- pseudomonas aeruginosa
- signaling pathway
- staphylococcus aureus
- biofilm formation
- current status
- candida albicans
- case control
- gene expression
- single cell
- pi k akt
- cystic fibrosis
- big data
- escherichia coli
- electronic health record
- machine learning
- artificial intelligence
- deep learning
- endoplasmic reticulum stress
- heat shock protein