The cytologic and immunohistochemical findings of pancreatic mixed acinar-endocrine carcinoma.
Rachel WhitehairEdward B StelowPublished in: Diagnostic cytopathology (2020)
The cytology of acinar cell carcinoma shares features with aspirates of other nonductal adenocarcinoma neoplasms of the pancreas. A clue to the diagnosis is that tumors show high Ki67 indices and a diagnosis of MAEC should be excluded anytime a diagnosis of Grade 2 or 3 well-differentiated neuroendocrine tumor or high-grade neuroendocrine carcinoma is in the differential.