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Primary lung cancer in women after previous breast cancer.

Tamar B NobelRebecca A CarrRaul CasoJennifer LivschitzSamuel NussenzweigMeier HsuKay See TanSmita SihagPrasad S AdusumilliMatthew J BottRobert J DowneyJames HuangJames M IsbellBernard J ParkGaetano RoccoValerie W RuschDavid R JonesDaniela Molena
Published in: BJS open (2022)
Differences in stage at diagnosis of lung cancer and treatment selection were observed between patients with and without a history of breast cancer. Overall, there were no statistically significant differences in genomic or oncogenic pathway alterations between the two groups, which suggests that lung cancer in patients who previously had breast cancer may not be affected at the genomic level by the previous breast cancer. The most important finding of the study was that a high percentage of women with lung cancer, regardless of breast-cancer history, did not meet the current USPSTF criteria for lung-cancer screening.
Keyphrases
  • metabolic syndrome
  • copy number
  • dna methylation
  • polycystic ovary syndrome
  • transcription factor
  • pregnant women
  • childhood cancer
  • smoking cessation