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Prediction of molecular mechanism of processed ginseng in the treatment of heart failure based on network pharmacology and molecular docking technology.

Tingting DaiJiyu GongShuying Liu
Published in: Medicine (2023)
The present study revealed that the treatment of HF with different processed ginseng products may be related to the regulation of the PI3K-Akt signaling pathway, TNF signaling pathway, apoptosis pathway, mTOR signaling pathway, etc, and that the key active ingredients may be concentrated in black ginseng, which provides a theoretical basis and direction for the further study of the mechanism of action of ginseng. This provides a theoretical basis and research direction for further in-depth study of its mechanism of action.
Keyphrases
  • signaling pathway
  • heart failure
  • molecular docking
  • pi k akt
  • oxidative stress
  • endoplasmic reticulum stress