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Low mortality oxidative stress murine chronic wound model.

Adriana C PanayiYori EndoMehran KarvarPrerana SensharmaValentin HaugSiqi FuBobin MiYang AnDennis P Orgill
Published in: BMJ open diabetes research & care (2021)
Overall, the two in vivo groups treated with the antioxidant enzyme inhibitors appeared to be arrested in the inflammatory stage of wound healing, while the Diabetic control group progressed to the maturation phase and ultimately remodeling. This model may be instrumental for the development of new wound therapeutics.
Keyphrases
  • wound healing
  • oxidative stress
  • type diabetes
  • dna damage
  • cardiovascular events
  • diabetic rats
  • induced apoptosis
  • heat shock protein
  • heat stress