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Myxoepithelioid tumour with chordoid features: a clinicopathological, immunohistochemical and genetic study of 14 cases of SMARCB1/INI1-deficient soft-tissue neoplasm.

Izumi KinoshitaKenichi KohashiHidetaka YamamotoYuichi YamadaTakeshi InoueKoichi HigakiNorihiro TeramotoYumi OshiroYasuharu NakashimaYoshinao Oda
Published in: Histopathology (2021)
The designation 'myxoepithelioid tumour with choroid features' (METC) was proposed as a tumour with intermediate malignancy controllable with appropriate treatment, including the entity of myoepithelioma-like tumour of the vulvar region. METC represents a novel and independent subset that is histologically, biologically and clinically distinct from already existing SMARCB1/INI1-deficient soft-tissue tumours.
Keyphrases
  • soft tissue
  • genome wide
  • gene expression
  • dna methylation
  • lymph node
  • early stage
  • combination therapy