Mortality after acute kidney injury and acute interstitial nephritis in patients prescribed immune checkpoint inhibitor therapy.
Megan L BakerYu YamamotoMark A PerazellaNazli DizmanAnushree C ShiraliNavid HafezJason WeinsteinMichael SimonovJeffrey M TestaniHarriet M KlugerLloyd G CantleyChirag R ParikhF Perry WilsonDennis G MoledinaPublished in: Journal for immunotherapy of cancer (2022)
In patients treated with ICI, mortality was higher in those with AKI unrelated to ICI but lower in those where the underlying etiology was AIN. Future studies could evaluate the association of biopsy-proven or biomarker-proven AIN with mortality in those receiving ICI therapy.
Keyphrases
- acute kidney injury
- end stage renal disease
- cardiovascular events
- cardiac surgery
- ejection fraction
- newly diagnosed
- chronic kidney disease
- prognostic factors
- stem cells
- respiratory failure
- current status
- coronary artery disease
- drug induced
- type diabetes
- acute respiratory distress syndrome
- mesenchymal stem cells
- patient reported
- extracorporeal membrane oxygenation
- smoking cessation