Levosulpiride-induced neuroleptic malignant syndrome in rheumatoid arthritis.
Devashish DesaiKartik GuptaRohit KumarAshutosh BiswasPublished in: BMJ case reports (2018)
A 53-year-old woman, known case of diabetes mellitus and rheumatoid arthritis, presented with a 4-day history of hyperthermia, rigidity, tremor and altered sensorium. She developed these symptoms after having been administered parenteral levosulpiride to control vomiting due to secondary adrenal insufficiency. We managed her as a case of life-threatening neuroleptic malignant syndrome (NMS) requiring mechanical ventilation, bromocriptine and other supportive care. She subsequently recovered and was discharged in a stable condition. To the best of our knowledge, this is the first documented case report describing levosulpiride-induced NMS.
Keyphrases
- rheumatoid arthritis
- case report
- mechanical ventilation
- healthcare
- high glucose
- diabetic rats
- acute respiratory distress syndrome
- intensive care unit
- disease activity
- interstitial lung disease
- drug induced
- palliative care
- parkinson disease
- deep brain stimulation
- quality improvement
- ankylosing spondylitis
- endothelial cells
- depressive symptoms
- metabolic syndrome
- physical activity
- respiratory failure
- systemic sclerosis
- adipose tissue
- stress induced
- chemotherapy induced