Antidiarrheal activity of Bridelia ferruginea bark methanolic extract involves modulation ATPases in mice and inhibition of muscarinic acetylcholine receptor (M3) and prostaglandin E2 receptor 3 (EP3) in silico.

Blessing Olugbamila OmolasoJulius Kolawole AdesanwoAhmed Adebayo IsholaAdeoti Gbemisola AdegokeFrancis O AkingbuleYetunde Ayoka IpadeolaKayode Ezekiel Adewole

Published in: Journal of complementary & integrative medicine (2021)

In view of these results, the observed antidiarrheal activity possibly occurs via the activation of ATPases activities and inhibition of M3 and EP3.

Keyphrases

oxidative stress
molecular docking
binding protein
metabolic syndrome
skeletal muscle