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Lower volume, more impairment: reduced cholinergic basal forebrain grey matter density is associated with impaired cognition in Parkinson disease.

Matthew J BarrettScott A SperlingJamie C BlairCody S FreemanJoseph L FlaniganMark E SmolkinCarol A ManningT Jason Druzgal
Published in: Journal of neurology, neurosurgery, and psychiatry (2019)
In de novo and more advanced PD, lower Ch4 density is associated with impaired global cognition, attention and visuospatial function.
Keyphrases
  • parkinson disease
  • white matter
  • working memory
  • deep brain stimulation
  • mild cognitive impairment
  • room temperature