The DELUX study: development of lung volumes during extubation of preterm infants.
Leonie PlastinaVincent D GaertnerAndreas D WaldmannJanine ThomannDirk BasslerChristoph Martin RüeggerPublished in: Pediatric research (2021)
This study is the first to examine the development of lung volumes during the entire extubation procedure including the impact of associated events. The extubation procedure significantly affects functional residual capacity with a loss of approximately 10 ml/kg at the time of extubation. Removal of adhesive tape is the major contributing factor to FRC loss during the extubation procedure. Functional residual capacity is regained within the first breaths after initiation of non-invasive ventilation and is further increased after turning the infant into the prone position.