Unraveling the role of epigenetic regulation in asymmetric cell division during plant development.

Asymmetric cell divisions (ACDs) are essential to generate different cellular lineages. In plants, ACDs regulate the correct formation of embryo, stomatal cells, apical and root meristems, and lateral roots. The current knowledge about the ACDs regulation suggests that, in addition to the function of key transcription factor networks, the epigenetic mechanisms play crucial roles. Therefore, here we highlight the importance of epigenetic regulation and chromatin dynamics for a suitable integration of signals and specification of cells that undergo ACD, polarization and segregation of cell components during ACDs, and for cell maintenance and cell fate establishment of both progenitor and daughter cells to ensure correct epigenetic memory or resetting of epigenetic marks for their proper cellular identities.