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Imaging the Vesicular Acetylcholine Transporter in Schizophrenia: A Positron Emission Tomography Study Using [ 18 F]-VAT.

Jodi J WeinsteinScott J MoellerGreg PerlmanRoberto GilJared X Van SnellenbergKenneth WenglerJiayan MengMark SlifsteinAnissa Abi-Dargham
Published in: Biological psychiatry (2024)
in several cortical and subcortical regions. These correlations provide preliminary evidence of cholinergic activity involvement in SCZ and, if replicated in larger samples, could lead to a more complete mechanistic understanding of psychosis and cognitive deficits in SCZ and the development of therapeutic targets.
Keyphrases
  • positron emission tomography
  • computed tomography
  • bipolar disorder
  • high resolution
  • pet ct
  • pet imaging
  • white matter
  • fluorescence imaging