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Plasma levels of GlycA, a pro-inflammatory glycoprotein biomarker, associate with an increased risk of microvascular complications in patients with type 2 diabetes (Zodiac-62).

Arno R BourgonjeAmarens van der VaartEke G GruppenHarry van GoorStephan J L BakkerMargery A ConnellyPeter R van DijkRobin P F Dullaart
Published in: Endocrine (2023)
Higher plasma GlycA is associated with an increased risk of developing microvascular complications in T2D patients. Altered N-glycan branching associated with acute-phase reactive proteins may represent a preferred biomarker of systemic low-grade inflammation in predicting diabetic complications.
Keyphrases
  • low grade
  • end stage renal disease
  • risk factors
  • high grade
  • newly diagnosed
  • ejection fraction
  • chronic kidney disease
  • type diabetes
  • oxidative stress
  • peritoneal dialysis
  • prognostic factors