Transcriptome Changes and Metabolic Outcomes After Bariatric Surgery in Adults With Obesity and Type 2 Diabetes.
Mamoon RashidAli Al QarniSaeed Al MahriSameer MohammadAltaf KhanMashan L AbdullahCynthia LeheReem Al AmoudiOmar S AldibasiAbderrezak BouchamaPublished in: Journal of the Endocrine Society (2023)
The changes in the transcriptome after bariatric surgery distinguish patients in whom diabetes enters complete remission from those who do not. The baseline transcriptome can contribute to the prediction of bariatric surgery-induced diabetes remission preoperatively.
Keyphrases
- type diabetes
- glycemic control
- bariatric surgery
- rna seq
- cardiovascular disease
- single cell
- gene expression
- weight loss
- genome wide
- end stage renal disease
- insulin resistance
- newly diagnosed
- metabolic syndrome
- prognostic factors
- disease activity
- chronic kidney disease
- rheumatoid arthritis
- dna methylation
- obese patients
- ulcerative colitis
- diabetic rats
- skeletal muscle
- weight gain
- high glucose
- body mass index
- stress induced
- patient reported