Genetic polymorphisms of the cobalamin transport system are associated with idiopathic recurrent implantation failure.
Han Sung ParkJung Oh KimHui Jeong AnChang Soo RyuEun Ju KoYoung Ran KimEun Hee AhnWoo Sik LeeJi Hyang KimNam Keun KimPublished in: Journal of assisted reproduction and genetics (2019)
Our study showed that the polymorphisms of TCN2 and TCblR are associated with RIF and are potential genetic predisposing factors for RIF among Korean women. Additionally, our findings support a potential role for TCN2 and TCblR in RIF among Korean women. However, further studies are required to investigate the role of the polymorphisms in those proteins and RIF because the roles of the TCN2 and TCblR polymorphisms in RIF are not clear.