Clonidine Overdose as an Unusual Cause of Heart Failure.
Jagdeep BhullarArti PatelJaagruthi ChitithotiFrederick VenterTheingi WinFowrooz JoolharPublished in: Journal of investigative medicine high impact case reports (2022)
Clonidine is used as an antihypertensive medication due to its effect on decreasing peripheral vascular resistance and therefore lowering blood pressure. Alpha antagonism in the medulla and the posterior hypothalamus causing a reduction in sympathetic activation allows for clonidine to be used as an effective off-label treatment for attention-deficit/hyperactivity disorder (ADHD). This is a case of a 28-year-old female with hypertension, ADHD, and depression who developed acute heart failure with significant troponemia after ingesting 30 pills of clonidine. We illustrate the possible rare diagnosis of systolic heart failure and coronary vasospasm secondary to clonidine overdose.
Keyphrases
- attention deficit hyperactivity disorder
- blood pressure
- heart failure
- acute heart failure
- autism spectrum disorder
- hypertensive patients
- left ventricular
- working memory
- heart rate
- coronary artery disease
- healthcare
- cardiac resynchronization therapy
- subarachnoid hemorrhage
- coronary artery
- sleep quality
- metabolic syndrome
- type diabetes
- insulin resistance
- blood brain barrier
- chemotherapy induced
- physical activity
- glycemic control