Group I introns: Structure, splicing and their applications in medical mycology.

Ronald Muryellison Oliveira da Silva Gomes Kássia Jéssica Galdino da Silva Raquel Cordeiro Theodoro

Published in: Genetics and molecular biology (2024)

Group I introns are small RNAs (250-500 nt) capable of catalyzing their own splicing from the precursor RNA. They are widely distributed across the tree of life and have intricate relationships with their host genomes. In this work, we review its basic structure, self-splicing and its mechanisms of gene mobility. As they are widely found in unicellular eukaryotes, especially fungi, we gathered information regarding their possible impact on the physiology of fungal cells and the possible application of these introns in medical mycology.

Keyphrases

healthcare
induced apoptosis
cell cycle arrest
genome wide
copy number
health information
endoplasmic reticulum stress
gene expression
dna methylation
transcription factor
social media